The Impact of Non-Alcoholic Fatty Liver Disease on Carotid Intima-Media Thickness: A Comprehensive Review
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- Category: Vol. 93, March 2025
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The Impact of Non-Alcoholic Fatty Liver Disease on Carotid Intima-Media Thickness: A Comprehensive Review, ISMAIL ANWAR, BESHOY MALAK ABDL SAYED, ALSHAIMAA ABOUL FOTOUH and MAHA SAYED HASSABALLAH
Abstract
Background: Early diagnosis of non-alcoholic fatty liver disease (NAFLD) is crucial for preventing both the fatal vas cular disorders associated with NAFLD and the underlying process of NAFLD. This study sought to determine the signifi cance of the relationships among NAFLD, metabolic syndrome (MS), and carotid intimal thickness (CIMT) as risk factors for ischemic cerebrovascular strokes. Aim of Study: This study was to assess the relation between NAFLD, metabolic syndrome, and carotid intimal thickness (CIMT), as well as detect the value of these relations as a risk factor for ischemic cerebrovascular strokes. Hence, neurooncological abnormalities should be interpret ed within the context of the clinical picture of hepatic patients. Material and Methods: A total of 102 participants were split into two groups for this case-control observational analyt ic study: 52 patients with NAFLD and metabolic syndrome and 50 control subjects. Measurements of carotid intimal thickness were made using the carotid duplex method. Results: Our results showed that NAFLD is significantly associated with increased carotid intimal thickness, as in our study, 23 patients (44.23%) of the case group had a risk of cer ebrovascular stroke compared to no such risk in the control group. From the 23 patients in the case group who had a risk of cerebrovascular stroke, 19 patients (79.2%) had NAFLD plus metabolic syndrome. Conclusion: NAFLD is a risk factor for cerebrovascular stroke, and this risk is significantly increased (five times) in the association of metabolic syndrome, so patients with fatty liv er should be investigated for other factors for ischemic strokes (cerebrovascular and cardiovascular) and guarded against them.