High Dietary Calcium and Weight Regulation in Mature and Premature Rats
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- Category: Vol. 80, December 2012
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High Dietary Calcium and Weight Regulation in Mature and Premature Rats,RADWAN S. FARAG, GHADA I. ISSA, GAMAL A. EL-BAROTY, OSAMA A. ABBAS and MOHAMAD T. MOHAMAD
Abstract
The present study was undertaken to find out a suitable dietary regime to maintain a lower prevalence of overweight or obesity by adjusting the diet components. Therefore, male albino rats were selected according to their ages and divided into two main groups, i.e., premature and mature groups. Each rat group was divided into 4 subgroups and each subgroup was fed on a diet of varied composition. Serum levels of lipids, calcium, phosphorous and testosterone were determined in addition to body weight measurement. The results indicate non-significant decrease of percentage of body weight gain in premature rats fed on high-calcium diets while significant decrease of percentage of body weight gain in mature rats fed on the same diet composition. The levels of serum HDL-C, LDL-C, triglycerides and testosterone were significantly decreased in premature rats fed high-calcium diets. In prema-ture rats, only rat subgroup fed on high calcium from milk, showed a significant decrease in serum cholesterol levels. Calcium and phosphorus levels exhibited non-significant change between premature rats. In mature rats, HDL-C and LDL-C data demonstrate non-significant changes while cho-lesterol and triglyceride levels were significantly decreased in rats fed high-calcium diet compared to control. Serum testosterone levels were significantly decreased in mature rats fed low-fat diets or low fat diets supplemented with high-calcium level. In general, one would suggest to consume low fat diet (4%) supplemented with high calcium from dry skimmed milk fortified with hydroxyapatite as suitable dietary program to avoid overweight.