Dexmedetomidine Versus Propofol for Sedation in Patients Undergoing Vitero-Retinal Surgery Under Peribulbar-Block,
/ 0
- Details
- Category: Vol. 84, March 2016
- Hits: 562
Dexmedetomidine Versus Propofol for Sedation in Patients Undergoing Vitero-Retinal Surgery Under Peribulbar-Block, HODA H. OKASHA, WAFAA S. HAMD, GEHAN M. OBAYA, ATEF K. SALAMA and MAYADA K. MOHAMAD
Abstract
Background and Aim: Vitreo-retinal surgeriesare preferred to be done under regional anesthesia with sedation which can be provided by many drugs with a relative risk of oversedation and disorientation, confusion or increased risk of respiratory depression. The aim of this study is to compare between dexmedetomidine and propofol as regard efficacy in achieving satisfactory level of sedation without hazards.
Subjects and Methods: 50 patients were received peri-bulbar block and randomely allocated to receive either dexme-detomidine (Group D, n=25) or propofol (Group P, n=25).
Results: The mean time to achieve RSS 3 was significantly longer in Group D (5.95±0.32) minutes than Group P (2.63± 0.37) minutes (p-value=0.004), themean intra-ocular pressure was significantly lower in Group D (Before 20.8±2.3 after 15±2.4) cm H2O than Group P (Before 23.3±6.1 after 21.8±6.2) cm H2O (p-value <0.001), the median pain score was signif-icantly lower in Group D than Group P during the first 6 hours postoperative.
Conclusion: Dexmedetomidine appears to provide more cardiovascular stability, more significant reduction of intraoc-ular pressure, better patient and surgeon satisfaction and less adverse events. Using dexmedetomidine there was a slightly longer duration in achieving RSS3 than propofol.