Congenital Anomalies in Giza, Egypt: A Cross-Sectional Study

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Congenital Anomalies in Giza, Egypt: A Cross-Sectional Study,GHADA M.H. ABDEL-SALAM, HANAN H. AFIFI, MAHA S. ZAKI, MONA S. AGLAN, IBRAHIM HEGAZY, AHMED TORKY, KHALED H. ABDULLA, SALLY TANTAWY, MAHMOUD Y. ISSA, MANAL MICHEAL, RANDA M. KAMAL, IBRAHIM EL-NEKHELY and SAMIA A. TEMTAMY

 

Abstract
Background: Enlarged vestibular aqueduct (EVA), the commonest radiological finding in children with sensorineural hearing loss is associated with variable auditory and vestibular symptoms.
Aim of the Work: Is to determine vestibular findings in patients with EVA.
Patients and Methods: 20 patients diagnosed as having sensorineural hearing loss and EVA as the study group, 20 healthy subjects matched for age and sex participated as the control group. Both groups underwent: Full history taking, General and neurological examination, Full ENT examination pure tone audiometry, tymanometry, high resolution computed tomography (HRCT), vestibular evoked myogenic potentials (VEMP), caloric test and computerized dynamic posturography.
Results: EVA was bilateral in 14 patients and unilateral in 6 patients. The VEMP amplitude of wave p13-n23 was higher in ears with EVA and it correlated positively with its size, p13-n23 latencies did not differ significantly from the control group, caloric test showed absent response in 4 patients, unilateral weakness in 6 patients and normal results in 10 patients, there was no statistical significant difference regarding computerized dynamic posturography results.
Conclusion: Results showed larger VEMP amplitude, which is indicative of third window lesion. Some patients showed Caloric test abnormalities which indicates a peripheral vestibular lesion. VEMP, caloric test and computerized dynamic posturography testing are effective in evaluating patients with EVA.

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